Field potential

Multi-unit frequency

Multi-unit action potentials

Multi-unit signal

Spikoscope - Browse and analyze electrophysiology recordings

Spikoscope & SpikoRT

Spikoscope is a computer program for browsing and analysis of electrophysiology recordings. Spikoscope can combine intracellular, extracellular, stimulus, and trigger signals. Extracellular signals can be processed to isolate field potentials, multiunit activity, and sorted spikes. Spikoscope generates analysis figures with recording trace filtering and compression and preset analysis models. Single channel tools include event detection and event frequency estimation. Cross-channel tools include event cross-correlogram and event triggered signal averaging. Synchrony of neuronal populations can be estimated quantitatively from one recording site or across a pair of sites.

SpikoRT is a real-time light version of Spikoscope. SpikoRT acquires extracellular signals from an analog input board, separates field potentials and multiunit activity through a set of digital filters, and computes instantaneous multi-unit frequency. SpikoRT displays both oscilloscope (1s) and paper chart like (15min) traces to monitor ongoing experiment.

Spikoscope and SpikoRT are free, open source softwares for scientific research and education. They are developed with Labview from National Instruments and are distributed under GNU Public License (GPL). Spikoscope and SpikoRT were composed by Ivan Cohen in the labs of Richard Miles, Fabrizio Gabbiani and Jeff Noebels. Some versions of Spikoscope included an early version of SpikeOMatic by Christophe Pouzat and Matthieu Delescluse. Special thanks to Edouard Yeramian, Norbert Ankri, Haleh Fotowat, Desdemona Fricker, Gilles Huberfeld, Liset Menendez de la Prida and Michael Bazelot for helpful discussions and feedback. Thanks to Sourceforge.net for hosting the web site.

Site updated may 2009